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Newer Antidepressant Medication:
Remeron (mirtazapine)


Remeron is a new medication which may relieve the symptoms of depression better than SSRIs or TCAs. Though Remeron has only been available in the United States since June 1996, it is thought to be particularly useful in reducing anxiety and sleep problems which often accompany depression. Researchers continue to investigate the effectiveness of Remeron.

Along with the many positive effects of Remeron, you may also experience some side effects. Side effects are unintended or undesirable reactions to medications. Most of the side effects you experience can be lessened with additional medications, dosage changes, or changes in your daily habits. Or, they may simply fade as your body adjusts to the medication. If you experience any side effects, contact your doctor or clinician right away and continue taking your medication.

It is also important to be aware of the risks of Remeron. The risks occur very rarely, but it is important to know what to look for, just in case.If you think you are experiencing one of the risks, contact your doctor or clinician or go to the emergency room right away!

Remember, because Remeron is such a new medication, all of the possible side effects and risks are not yet known. If you experience any troublesome effects (in addition to those listed below) after you start taking Remeron, be sure to talk to your doctor about it.

Most common side effects dizziness, drowsiness, weight gain
Occasional side effects dry mouth, constipation
Risks agranulocytosis, hypomania

Most common side effects

 
  Dizziness

If you feel dizzy when you sit or stand up quickly, there are some precautions that you can take to avoid injury. Get up very slowly from a laying or sitting position and make sure you have something to hold onto as you rise. Then, wait a moment or two before you start walking.
 
Drowsiness

When you first begin taking Remeron, you may feel drowsy all of the time, even if you 've had a good night 's sleep. You might move around more slowly, be less coordinated, and nod off more. This side effect should wear off after a few weeks. In the meantime, be sure not to drive a car or operate other heavy machinery while you are feeling drowsy.
 
Weight gain

Remeron may cause you to gain weight. Your doctor or clinician can help you monitor your weight and suggest a healthy diet and exercise program for you if weight gain is a concern.
 

Occasional side effects

 
Dry mouth

Some people taking Remeron experience dry mouth. Although dry mouth may not go away completely, it usually gets better with time. Dry mouth may be relieved by sucking on hard candy or crushed ice, drinking plenty of fluids, or eating frozen grapes.
 
Constipation

Remeron can sometimes cause constipation. This side effect usually does not go away, but you can learn how to control it by increasing the amount of high fiber foods in your diet, such as breads, fruits, and vegetables, and bran. It also helps to exercise regularly and drink plenty of fluids. If constipation is still a problem, your doctor may recommend a laxative or fiber product, or may prescribe an additional medication to reduce the side effect.
 

Risks

 
Agranulocytosis

In preliminary clinical trials, less than .001% of people taking Remeron developed a condition known as agranulocytosis, which is a decrease in the number of white blood cells. Agranulocytosis is a potentially deadly condition because it makes your body more susceptible to infection. Symptoms of agranulocytosis include fever, sore throat, and flu-like symptoms. As more people are prescribed Remeron, we can determine the frequency of agranulocytosis as a risk of the medication.
 
Hypomania

Remeron may cause an increase in mood called hypomania. Symptoms of hypomania include euphoria, racing thoughts, pressured speech, and excessive energy. If you notice any of these changes, contact your doctor right away. S/he can help you determine if your change in mood seems unusual.
 


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